Immune Deficiency vs. Immune Dysregulation: How do we begin to wrap our heads around these patients?

Lisa R. Forbes Satter, MD, is an Associate Professor of Pediatrics, Section of Immunology, Allergy, and Retrovirology at Baylor College of Medicine and Texas Children’s Hospital, Clinical Director of the William T. Shearer Texas Children’s Center for Human Immunobiology, Director of the Jeffrey Modell Foundation Center for Education and Research, and Medical Director of the Texas Children’s Hospital Infusion Center. Dr. Forbes Satter’s primary clinical and research focuses on immune deficiency and immune dysregulation, STAT transcription factor signaling defects in natural killer cells as well as novel gene discovery and therapeutic modulation in immune mediated disease. She has >70 peer reviewed publications as well as NIH and foundation funding. She is the 2019 recipient of the Norton Rose Fullbright award for excellence in Teaching and Education and the 2020 recipient of the Baylor College of Medicine Department of Pediatrics Young Investigator Award. Dr. Forbes Satter has dedicated her academic career to translational research and clinical care of patients with rare immunologic disease through the development of multidisciplinary translational programs such as the Texas Children’s Hospital Immune Disorder Clinic Network which connect the clinical care with novel disease and therapeutic discovery. Her work is geared toward understanding the mechanism of immune dysregulation to translate this knowledge into viable targeted and sustainable therapies.

Learning Objectives:

  1. Describe how the field of inborn errors of immunity has evolved over the last 20 years
  2. Discuss disease presentation for a variety of immune disorders and highlight genetic basis and inheritance patterns of well-defined primary immunodeficiency syndromes
  3. Elucidate new ways to study therapeutic options in rare disease


  • Lisa R. Forbes Satter, MD

This seminar was delivered as a Pediatric Grand Rounds Lecture at Children’s Hospital of Philadelphia, on January 4, 2023.

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Course Includes

  • 1 Lesson
  • Course Certificate
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